Clinical Trials at the PEI Cancer Treatment Centre

Clinical trials are research studies that involve people. A clinical trial tests new medications and treatments to help determine if they work. Many advances in cancer treatment and improvements in cure and survival rates have resulted from clinical trials.

The PEI Cancer Treatment Centre offers the following types of trials, when available:

Cancer treatment trials
Treatment trials are designed to answer questions about new treatments or ways of using an existing treatment better. This could include the use of new drugs or vaccines, ways to do surgery or give radiation therapy, or combinations of treatments.

Quality-of-life or supportive care trials
Quality-of-life trials are always looking for ways to increase comfort and/or quality of life for people with cancer and cancer survivors. These trials may look at ways to manage things like fatigue, pain, nausea, or any other cancer-related symptom.


Who can join a clinical trial?

Patient safety is the primary concern at the PEI Cancer Treatment Centre. Each clinical trial has its own criteria a patient must meet to be enrolled. This ensures the safety of the patient while on the trial and ensures the results of the trial are accurate.

The following is an example of common criteria for entering a trial:

  • having a certain type or stage of cancer
  • having received a certain kind of therapy in the past
  • being in a certain age group.

Participating in a clinical trial is your choice. Discuss your options with your doctor, clinical trial nurses, and people close to you to make an informed decision.


What clinical trials are currently being offered at the PEI Cancer Treatment Centre?

Below are the Clinical Trials that are currently being offered at the PEI Cancer Treatment Centre:


Trial name:  CO.27 – A Phase III, Randomised, International Trial Comparing mFOLFIRINOX Triplet Chemotherapy to mFOLFOX for high Risk Stage III Colon Cancer in Adjuvant Setting

Status: Open for recruitment

Trial name:  CRC 6 – A Phase III Trial of 6 versus 12 Treatments of Adjuvant Folfox Plus Celecoxib or Placebo For Patients With Resected Stage III Colon Cancer

Status: closed to recruitment – patients on follow-up


Trial name:  MAC 21 – A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: THE ABC TRIAL

Status: closed to recruitment – patients on follow-up

Trial name:  MAC 13 – Adjuvant, Lapatinib and/or Trastuzumab Treatment Optimisation Study A Randomized, Multi-Centre, Open-Label, Phase III Study of Adjuvant Lapatinib, Trastuzumab, Their Sequence and Their Combination in Patients with HER2/ErbB2 Positive Primary Breast Cancer

Status: closed to recruitment – patients on follow-up

Trial name:  MAC 15 – A Phase III Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy Plus or Minus Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less. RxPONDER: A Clinical Trial Rx For Positive Node, Endocrine Responsive Breast Cancer

Status: closed to recruitment – patients on follow-up

Trial name:  MA 32 – A Phase III Randomized Trial of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer

Status: closed to recruitment – patients on follow-up


Trial name:  BR.31 – A Phase III Prospective Double-Blind Placebo-Controlled Randomized Study of Adjuvant MEDI4736 in Completely Resected Non-Small Cell Lung Cancer

Status:  closed to recruitment – patients on follow-up


Where can I get more information on clinical trials?

For more information on clinical trials, visit the following websites or contact the clinical trials coordinator.

Clinical Trials Coordinator
Katherine Grant-Smith
PEI Cancer Treatment Centre

Telephone: 902-894-2935
Fax:  902-894-0132


Published date: 
February 22, 2023
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